What is Autism ?

Autism is a developmental disability characterized by impairments in social interaction, in verbal and non-verbal communication and a pattern of repetitive, stereotypic activities. Autism is the most common condition in a group of developmental disorders known as Autism Spectrum Disorders (ASDs). Other ASDs include Asperger syndrome, Rett syndrome, childhood disintegrative disorder and Pervasive Developmental Disorder-Not Otherwise Specified(PDD-NOS). Autism represents the most extreme form of PDD. Experts estimate that 3-6 children out of every 1000 children will have autism. Males are 4 times more likely to have autism than females.Autism is a neurodevelopmental spectrum disorder, and although it is defined by a certain set of behaviors, children and adults with autism can exhibit any combination of these behaviors in any degree of severity.

Autism is a complex developmental disability that typically appears during the first three years of life and is the result of a neurological disorder that affects the normal functioning of the brain, impacting development in the areas of social interaction and communication skills. The hallmark feature of autism is impaired social interaction. It is a sensory integration and communication disorder. Sensory system of autistics is quite different from the sensory system of other people, since certain stimulations can affect an autistic differently than a non-autistic. Autism is a complex neurobiological disorder of development that lasts throughout a person’s life. It is called a developmental disability because it usually starts before age 3, in the developmental period.

 

 


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Signs & Symptoms of Autism
 Autism is characterized by difficulties in social interactions, problems with verbal and non-verbal communication, and repetitive behaviours or narrow obsessive interests. Some individuals mildly affected may exhibit only slight delays in language and greater challenges with social interactions. They may have difficulty initiating and/or maintaining a conversation. Their communication is often described as talking at others instead of to them.

Some children with autism are particularly sensitive to sound, finding even the most ordinary daily noises painful. Because different people with autism have different features or symptoms, autism is regarded as a spectrum disorder-a group of disorders with a range of similar features.

A number of behavioural symptoms of autism are observable by 18 months of age. Children with autism appear to have a higher than normal risk for certain co-existing conditions, including fragile X syndrome (which causes mental retardation), tuberous sclerosis (in which tumours grow on the brain), epileptic seizures, Tourette syndrome, learning disabilities, and attention deficit disorder. For reasons that are still unclear, about 20 to 30 percent of children with autism develop epilepsy by the time they reach adulthood. While people with schizophrenia may show some autistic-like behaviour, their symptoms usually do not appear until the late teens or early adulthood.

 

People with autism also process and respond to information in unique ways. In some cases, aggressive and/or self-injurious behavior may be present. Persons with autism may also exhibit some of the following traits: 
• Resistance to change 
• Difficulty in expressing needs, using gestures or pointing instead of words 
• Repeating words or phrases in place of normal, responsive language 
• Laughing (and/or crying) for no apparent reason showing distress for reasons not apparent to others 
• Preference to being alone 
• Difficulty in mixing with others 
• Little or no eye contact 
• Unresponsive to normal teaching methods 
• Obsessive attachment to objects 
• No real fears of danger 
• Noticeable physical over-activity or extreme under-activity 
• Uneven gross/fine motor skills 
• Non responsive to verbal cues; acts as if deaf, although hearing tests in normal range.
• Many children with autism engage in self abusive behaviour such as biting or head banging.
• They tend to start speaking later than other children.
• Many of them may have reduced sensitivity to pain.
• Abnormally sensitive to sound, touch or other sensory stimulation.

Causes of Autism
There is no known single cause for autism, but it is generally accepted by the medical community that it is caused by abnormalities in brain structure or function. Brain scans show differences in the shape and structure of the brain in autistic versus non-autistic children. Studies suggest that people with autism have abnormal levels of serotonin or other neurotransmitters in the brain. These abnormalities suggest that autism could result from the disruption of normal brain development early in fetal development caused by defects in genes that control brain growth and that regulate how neurons communicate with each other. It’s likely that both genetics and environment play a role. Recent studies strongly suggest that some people have a genetic predisposition to autism. In families with one autistic child, the risk of having a second child with the disorder is approximately 5 percent, or one in 20. Autism tends to occur more frequently than expected among individuals who have certain medical conditions, including Fragile X syndrome, tuberous sclerosis, congenital rubella syndrome, and untreated phenylketonuria (PKU). 

Some harmful substances ingested during pregnancy have also been associated with an increased risk of autism. Whatever the cause, it is clear that children with autism and PDD are born with the disorder or born with the potential to develop it.

 

Diagnosis of Autism
Autism varies widely in its severity and symptoms and may go unrecognized, especially in mildly affected children or when it is masked by more debilitating handicaps. Doctors rely on a core group of behaviors to alert them to the possibility of a diagnosis of autism. These behaviors are: 
• impaired ability to make friends with peers
• impaired ability to initiate or sustain a conversation with others
• absence or impairment of imaginative and social play
• stereotyped, repetitive, or unusual use of language
• restricted patterns of interest that are abnormal in intensity or focus
• preoccupation with certain objects or subjects
• inflexible adherence to specific routines or rituals

Doctors will often use a questionnaire or other screening instrument to gather information about a child’s development and behavior. Autism is a complex disorder. A comprehensive evaluation requires a multidisciplinary team including a psychologist, neurologist, psychiatrist, speech therapist, and other professionals who diagnose children with ASDs. Children with some symptoms of autism, but not enough to be diagnosed with classical autism, are often diagnosed with PDD-NOS. Children with autistic behaviors but well-developed language skills are often diagnosed with Asperger syndrome. Children who develop normally and then suddenly deteriorate between the ages of 3 to 10 years and show marked autistic behaviors may be diagnosed with childhood disintegrative disorder. Girls with autistic symptoms may be suffering from Rett syndrome, a sex-linked genetic disorder characterized by social withdrawal, regressed language skills, and hand wringing. 

Treatment for Autism
Currently there is no definitive, single treatment for ASDs. However there are a variety of ways to minimize symptoms and maximum learning. In some cases, appropriate treatment can help people with autism function at near normal levels. The ideal treatment plan coordinates therapies and interventions that target the core symptoms of autism: impaired social interaction, problems with verbal and nonverbal communication, and obsessive or repetitive routines and interests. Most professionals agree that the earlier the intervention, the better. 

Educational/Behavioral interventions: Therapists use highly structured and intensive skill-oriented training sessions to help children develop social and language skills. Family counselling for the parents and siblings of children with autism often helps families cope with the particular challenges of living with an autistic child.
• Speech language therapists can help people with autism improve their general ability to communicate and interact with others effectively, as well as develop their speech and language skills.
• Occupational therapists can help find ways to adjust tasks and conditions that match their needs and abilities.
• Physical therapists design activities and exercises to build motor control and improve posture and balance.
• Medications: Doctors often prescribe an antidepressant medication to handle symptoms of anxiety, depression, or obsessive-compulsive disorder. Anti-psychotic medications are used to treat severe behavioral problems. Seizures can be treated with one or more of the anticonvulsant drugs. Stimulant drugs, such as those used for children with attention deficit disorder (ADD), are sometimes used effectively to help decrease impulsivity and hyperactivity.


Medications may include
• Selective serotonin reuptake inhibitors a group of antidepressents, to treat compulsive obsessive behaviour , anxiety and aggressive behaviour.
• Tricyclics another group of antidepressents to treat depression and compulsive behaviour.
• Psychoactive or antipsychotic medications may decrease hyperactivity.
• Anti-anxiety drugs help relieve anxiousness and panic disorders associated with autism.

 

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Article Contributed By: Shaonli Dasgupta

 

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