Why do arteries get blocked ?

Arteries are responsible for the bringing in of blood, rich in oxygen and nutrients, from the heart to all the other parts of the body. These arteries are like thin pipes which with the process of ageing start getting clogged – a process medically termed as atherosclerosis. When the cholesterol (the fatlike molecule inside our body) level starts increasing, it affects our blood vessels i.e. the veins and the arteries, which are responsible for carrying blood. A sticky matter called plaque that comprises primarily of cholesterol along with calcium, and fibrous tissue begins to accumulate on the walls of the arteries causing them to harden. With an excessive amount of accumulation, blood flow can eventually stop – which can be fatal. This increases the possibility of a heart attack or stroke and hence need to be treated immediately.

If the arteries which are responsible for carrying blood to the heart are affected, the chances of heart attack or angina increases. Heart attack is also termed as myocardial infarction in medical science. Myocardial is “related to the heart muscle” and Infarction is “the death of the organ”. Thus the coined term means heart attack due to the stopping of the blood flow to the heart. Angina is the situation when the flow is alarmingly low. A blocked artery to the brain can lead to a stroke, to the kidney can cause a kidney failure and to the limbs (arms and legs) can result to amputation (removing off).

 

 


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Causes of Atherosclerosis
• Smoking
• Obesity
• Inadequate physical activity
• Diabetes
• High blood pressure
• High cholesterol or hypercholesterolemia
• Consumption of fatty foods like chocolate, fried stuff, ice creams, red meat.
• Stress
• Excessive alcohol
 

Once atherosclerosis is diagnosed, immediate precautions must be taken to prevent damages. These include a healthy diet comprising of fruits and vegetables, regular exercises and bidding farewell to smoking. In addition to these, regular checkups with the physicians are necessary to ensure that infarction has not happened. Patients with atherosclerosis are more proned to a heart attack or stroke. CAD or coronary artery disease is the situation when the coronary arteries get severely blocked, thus stopping the oxygen to the heart and leading to heart attack. Statistics have shown that in this year almost 1.1 million Americans suffered from this disease. Angioplasty or the stent procedeor is the most well known form of treatment of the artery disease. In this procedeor a long, thin and supple pipe or catheter is inserted into the blocked artery through a small puncture. The catheter has a small balloon attached to it which being inflated and deflated pushes the plaque against the artery walls. This widens the artery after which the doctor immerses a small metal tube called stent into this area to keep it open. The stent remains in the artery and allows a free flow of blood.

Symptoms of CAD
• Sudden chest pain
• Short breath
• Abnormal pulse rate i.e. fast, slow, irregular or weak than normal
• Paralysis on one side of the body
• Swollen abdomen and limbs.

However, angioplasty is not a fool proofsolution to this problem and the blockage may recur even after this. This situation is known as restenosis . It has been seen that in almost 50% cases re narrowing or restenosis occurs. To avoid this the Cypher Sirolimus-eluting Coronary stent is used that opens the artery and releases an unique medication which prevents the re blocking. 

Leg artery or lower extremity occlusive disease is caused by the inadequate blood flow from the heart to the limbs. 1 out of every 3 aged people suffer from this. The pain occurs when a person is walking. It can be felt in the hips, upper legs, thighs, knees or shins.

Symptoms
The most common symptom is intermittent claudication or a pain occurs when the person walks and disappears as he rests. Apart from pain, the person might also experience weakness in the leg, or cramps or heaviness. At an acute stage the pain occurs even if the person is relaxing.

 

Treatment
• Medicines which contain cholesterol and blood pressure lowering properties are prescribed to the patient. There is also a need to take medicines that minimizes blood clots thus lowering the chance of clots blocking the arteries. Drugs like cilostazol(Pletal), and clopidogrel (Plavix) are generally given.
• Physical activity or walking is also prescribed to the ptients. A regular walking exercise helps in recovering from the discomfort.
• Bypass Surgery is another method of treatment. With the aid of this surgery an alternative route is grafted around the blocked artery. A fine, thin tube or a vein from the patient’s body is sewn above and below the affected area– making a new path for the blood flow.
• Endarterectomy is the process by which the doctors make a small slit on the leg and removes the accumulated plaque from the inner lining of the artery. This makes the artery plaque free and restores the flow of blood.

• Angioplasty is performed in advanced cases of leg artery disease. A stent is inserted in the artery to widen it and allow the blood to flow.
• Thrombolytic therapy is used when the blockage occurs due to a blood clot. A clot dissolving medicine is introduced by the doctor to open the artery.
• Amputation or the removal of the limb is the last resort sought by the doctors if the patient has developed gangrene. However, more than 90% of the patients who visit the vascular specialists can avoid amputation or limit it to a small portion on their foot or toes.

 

Hence it is important for us to live a healthy lifestyle and prevent ourselves from getting affected by this disease. Even if it is diagnosed, proper medical attention is a must – because only with effective treatment one can get back to his normal life and enjoy!

A variety of tests are peformed to confirm the leg artery disease. They include an Ankle - brachial index or ABI, a test that is done to compare the blood pressure of the arms and legs and Blood test to check the cholesterol level. In addition to this a few other tests are also performed to determine the extent of the damage. These include Duplex ultrasound, pulse volume recording, magnetic resonance angiography and angiography. 
• High frequency sound waves are used in Duplex ultrasound to check the blood flow in the arteries and look for abnormalities. 
• Pulse volume recording records the blood volume at different points in the leg.
• Magnetic resonance angiography or MRA takes the hlp of radio waves and magnetic fields to determine the blockages in the arteries.
• Finally, angiography uses Xray imaging with contrast dyes to determine the damages.

 

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Article Contributed By: Sukanya Banerjee

 

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