What is Cellulitis ?

Cellulitis is a bacterial infection that affects the skin. It occurs as an inflammation in the connective tissues beneath the layer of skin and is a potentially dangerous condition. It appears as a swollen, red area of skin that feels warm and painful, and may spread rapidly.

Cellulitis usually occurs on a part of the skin that is broken or has an abrasion due to a trauma or injury. It can develop rapidly within twenty-four hours or can take days to develop. In most cases, medical treatment using antibiotic therapy can clear cellulitis within 10 days. However, it can take months to cure in more serious cases, and can result in severe debility or even death if left untreated. The presence of cellulitis could mean a deeper, more serious infection of the inner layers of skin. The bacteria can spread rapidly once it enters the skin layers to the lymph nodes and the bloodstream and spread throughout your body. In rare cases, the infection can also spread to the deep layer of tissue called the fascial lining.

Types of Cellulitis
Periorbital cellulitis is an infection of the eye socket and the soft tissues around the eye. It is usually caused by an infection spreading from the membrane covering the outer part of the eye (conjunctivitis or pink eye) or from the nose and throat (a bacterial infection of the nose or the sinuses). This can lead to red, swollen eyes, can be quite painful and is a serious infection. This kind of cellulitis is more common among children than adults.

 


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Erysipelas is an acute infection of the most superficial layers of the skin usually caused by the streptococcus bacteria. This disease most frequently affects infants, young children, and the elderly. Pink-to-red lesions that spread rapidly and are warm to the touch appear on the face, arms and legs.

Clostridial cellulitis is a disease that is usually caused by clostridium perfringens and is characterized by the accumulation of gas along the soft tissues. The gas creates bubbles under the skin and sometimes in the blisters themselves causing the skin to crack when pressed. Initially the infected area is painful, but as the skin dies, the nerves stop working and the area loses sensation. Synergistic necrotizing cellulitis is a rapidly progressive infection of subcutaneous tissues and muscles.

 

Necrotizing fasciitis is commonly known as "flesh-eating bacteria" and is a rare infection of the deeper layers of skin and subcutaneous tissues (fascia). Mortality is nearly 100 percent in this condition if not properly treated. Correct diagnosis and early treatment of this disease is therefore of extreme importance.

Causes
Cellulitis is caused by different types of bacteria entering by way of a break in the skin. Group A streptococcus and staphylococcus are the most common of these bacteria that are part of the normal flora of the skin that cause no actual infection until the skin is broken.

Predisposing conditions for cellulitis include
• insect bite
• animal bite
• skin rash
• recent surgery
• athlete’s foot
• dry skin
• eczema
• burns & boils
• weakened immune systems

Cellulitis can occur anywhere on your body but the most common places are the legs especially near the shins and ankles. Sometimes cellulitis develops even when there is no apparent breaking of the skin. This is because the bacteria can enter through microscopic openings in the skin.

Risk factors
Following are some of the factors that can place you at greater risk of developing cellulitis:
• Age As you get older, your bodily functions slow down and your circulatory system becomes less effective in delivering blood and the infection-fighting white blood cells to all areas of your body. This can cause cellulitis in the weakened areas.
• Weak immune system Illnesses, such as AIDs and leukemia that result in a weakening of your immune system, leave you more susceptible to infections such as cellulitis.
• Immune-suppressing drugs Intake of certain drugs like prednisone or cyclosporine can leave you more susceptible to infections.
• Diabetes diabetes not only increases your blood sugar level but also impairs your immune system and increases your risk of infection. Diabetes causes impairment of blood circulation in legs leading to foot ulcers that commonly become infected.
• Chickenpox and shingles These viral diseases result in blisters which break providing a gap in the skin which bacteria can enter through.
• Lymphedema this condition causes chronic swelling of your arms or legs, and swollen tissue may crack leaving your skin vulnerable to bacterial infection.
• Athlete’s Foot Recurrent fungal infection of your feet or toes can cause cracks in your skin and increase your risk of bacterial infection.
 

 

Diseases that affect blood circulation in the legs and feet, such as chronic venous insufficiency and varicose veins are also risk factors for cellulitis. Cellulitis is also prevalent amongst dense populations (military quarters) sharing hygiene facilities and common living quarters.

Symptoms
The affected skin may become red, inflamed, painful and tender to the touch. It is usually accompanied by fever, chills and a general feeling of ill-health.

Diagnosis
It is important to identify and treat cellulitis early because it is a serious infection that spreads rapidly throughout your body. A doctor will check the appearance of your skin; suggest blood tests or a wound culture to rule out a blood clot or other similar conditions.
 

Treatment
Since it is a bacterial infection, the usual course of the treatment is oral antibiotics. Some bacteria are resistant to some antibiotics, so a change in antibiotic may be needed if the infection does not improve with the first antibiotic. Usually antibiotics are prescribed for 10 days and if the condition does not clear up or show signs of improvement, the drug may be changed. If the infection proves resistant to oral drugs, intravenous (IV) antibiotics may be necessary.

Prevention
To prevent cellulitis and other infections, take the following precautions if you have a skin wound:
• Wash your wound daily with soap and water.
• Apply an antibiotic cream or ointment on the wound to prevent infection.
• Apply bandage to your wound to keep it covered and safe from infections.
• Change bandages often. Do not let it become wet or soggy.
• Watch for signs of infection. Redness, pain and drainage are cause for concern infection and need immediate medical evaluation.
• In addition, follow good skin-care routine:
Moisturize your skin regularly. Lubricating your skin helps prevent cracking and peeling.
Trim your fingernails and toenails carefully. Do not injure the surrounding skin.
Protect your hands and feet with appropriate footwear and gloves.
Promptly treat any superficial skin infections such as athlete's foot.
Wear protective equipment during certain activities such as gardening.

 

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Article Contributed By: Sukanaya Banerjee

 

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